Mechanisms of Protein Folding pdf epub fb2

Mechanisms of Protein Folding by - pdf epub fb2 djvu

Author: -
Title: Mechanisms of Protein Folding
ISBN: 0199637881
ISBN13: 978-0199637881
Other Formats: txt rtf lrf mbr
Pages: 433 pages
Publisher: Oxford University Press; 2 edition (December 15, 2000)
Language: English
Size PDF version: 1710 kb
Size EPUB version: 1577 kb
Category: Science & Math
Subcategory: Biological Sciences

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The process by which newly synthesized polypeptide chains become their final 3-dimensional protein forms is clearly explained, providing students and researchers of various backgrounds with both a conceptual and technical understanding of the subject. The new Second Edition incorporates the significant improvements in the field such as advances in interpreting observed kinetic data, the development of technology to observe fast folding reactions, the molten globule state, and the vital role of chaperone proteins in protein folding. The emphasis on experimental approaches has been maintained but this edition does so within the explicit context of simulations and energy surfaces. New discoveries of the central importance of protein folding and unfolding reactions in biology and medicine (including mutation and 'misfolding') are carefully explored. Three case studies elucidate the difficulties of studying protein folding in vivo.

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